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doi: 10.1038/nrd2909 Summary Keywords antibody therapies, CD38 monoclonal antibodies, IgG Fc receptors, ectoenzymatic activity, multiple myeloma Citation Horenstein AL, Faini AC, Morandi F, Ortolan E, Storti P, Giuliani N, Richardson PG and Malavasi F (2025) Monoclonal anti-CD38 therapy in human myeloma: retrospects and prospects